T1–T2 microscale correlation relaxometry for in situ high-pressure nuclear magnetic resonance

Thomas Meier; Meng Yang; Yishan Zhou; Yunhua Fu; Rui Zhang; Ziliang Wang; Tianyao Zheng; Rajesh Jana; Takeshi Nakagawa

doi:10.1063/5.0320998

Volume 11 Issue 5

Sep. 2026

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Thomas Meier, Meng Yang, Yishan Zhou, Yunhua Fu, Rui Zhang, Ziliang Wang, Tianyao Zheng, Rajesh Jana, Takeshi Nakagawa. T1–T2 microscale correlation relaxometry for in situ high-pressure nuclear magnetic resonance[J]. Matter and Radiation at Extremes, 2026, 11(5): 057803. doi: 10.1063/5.0320998

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Thomas Meier, Meng Yang, Yishan Zhou, Yunhua Fu, Rui Zhang, Ziliang Wang, Tianyao Zheng, Rajesh Jana, Takeshi Nakagawa. T₁–T₂ microscale correlation relaxometry for in situ high-pressure nuclear magnetic resonance[J]. Matter and Radiation at Extremes, 2026, 11(5): 057803. doi: 10.1063/5.0320998

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T₁–T₂ microscale correlation relaxometry for in situ high-pressure nuclear magnetic resonance

doi: 10.1063/5.0320998

Thomas Meier^{1, 2
,
,
,},
Meng Yang²,
Yishan Zhou²,
Yunhua Fu^{2, 3},
Rui Zhang^{2, 3
,},
Ziliang Wang²,
Tianyao Zheng²,
Rajesh Jana^2
,,
Takeshi Nakagawa^2
,

1.
Shanghai Key Laboratory MFree, Institute for Shanghai Advanced Research in Physical Sciences, Pudong, Shanghai 201203, China
2.
Center for High-Pressure Science and Technology Advanced Research, Beijing, China
3.
School of Earth and Space Sciences, Peking University, Beijing, China

More Information

Corresponding author: a)Author to whom correspondence should be addressed: thomas.meier@sharps.ac.cn
Received Date: 2026-01-05
Accepted Date: 2026-06-03

Available Online: 2026-09-28

Publish Date: 2026-09-01

Abstract

Abstract

Over the last decade, frequency-domain in situ high-pressure nuclear magnetic resonance (NMR) spectroscopy in diamond anvil cells (DACs) has been employed as a structural and electronic probe of condensed matter systems at pressures well into the megabar range. However, extensive spin interactions and sample heterogeneities under pressure often lead to significant spectral overlap, inhibiting independent observation of chemically similar spin subspecies in the same sample. In this work, we introduce a time-domain relaxometry framework specifically suited for DAC experiments. Experimental flexibility and operational robustness are benchmarked on three hydrogen-rich molecular solids at pressures up to 72 GPa. We demonstrate that T₁–T₂ relaxometry can separate distinct proton populations in relaxation space even when the corresponding frequency-domain spectra are strongly broadened and overlapping, thereby establishing a practical route to relaxation-based high-pressure NMR analysis in molecular solids.

The authors have no conflicts to disclose.
Conflict of Interest
Thomas Meier: Conceptualization (equal); Data curation (equal); Formal analysis (equal); Funding acquisition (equal); Investigation (equal); Methodology (equal); Project administration (equal); Resources (equal); Software (equal); Supervision (equal); Validation (equal); Visualization (equal); Writing – original draft (equal); Writing – review & editing (equal). Meng Yang: Conceptualization (equal); Formal analysis (equal); Investigation (equal); Validation (equal); Visualization (equal); Writing – review & editing (equal). Yishan Zhou: Data curation (equal); Formal analysis (equal); Investigation (equal); Methodology (equal); Validation (equal); Visualization (equal); Writing – review & editing (equal). Yunhua Fu: Data curation (equal); Investigation (supporting); Methodology (supporting); Writing – review & editing (equal). Rui Zhang: Investigation (supporting); Visualization (equal); Writing – review & editing (equal). Ziliang Wang: Investigation (supporting); Software (supporting); Writing – review & editing (supporting). Tianyao Zheng: Software (supporting); Writing – review & editing (supporting). Rajesh Jana: Methodology (supporting); Writing – original draft (supporting); Writing – review & editing (supporting). Takeshi Nakagawa: Conceptualization (supporting); Investigation (supporting); Software (supporting); Writing – original draft (supporting); Writing – review & editing (supporting).
Author Contributions
Meng Yang and Yishan Zhou contributed equally to this work.
T.M., M.Y., and Y.Z. were responsible for the concept of this study. Y.F., R.Z., Z.W., and T.Z. were responsible for its preparation. T.M., R.J., and T.N. carried out the experiments. T.M., M.Y., Y.Z., and Y.F. performed the data analysis. T.M., M.Y., Y.Z., R.J., and T.N. wrote the manuscript.
The Python script used for data analysis in this study is available from the corresponding author upon reasonable request.

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References(31)

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